The 1,150-kilometre (710 mi) Quebec City–Windsor Corridor is the most densely-populated and heavily-industrialized region of Canada. With over 17 million people (2001 Census), it contained 56.8% of the Canadian population and three of the six largest metropolitan areas in the country. In its relative importance to the country's economic and political infrastructure, it has many similarities to the Northeast megalopolis in the United States.

The name is derived from the names of the cities at each end and was first popularized by Via Rail, which runs frequent passenger rail service on what it simply calls "The Corridor". Much like "Northeast Corridor" in the United States, the Quebec City–Windsor Corridor name has been expanded to refer to the geography and demography of the region the corridor traverses.